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Guillain-Barré Syndrome

Guillain-Barré Syndrome is treated at 澳门银河平台 Neurology's Neuromuscular Clinic.

About Guillain-Barré Syndrome

Definition

Guillain-Barré syndrome is a rare problem that causes the immune system to attack the nerves. This results in muscle weakness. It can range from mild to life-threatening. Most people will get better.

Nervous System
CNS 和 PNS
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原因

The exact cause is not known. In some people, it is triggered by a recent infection.

Risk Factors

Guillain-Barré syndrome is more common in men. The risk gets higher with age. Other things that may raise the risk are:

  • Recent infection
  • Stress-related disorder
  • Recent vaccination (rare)

症状

Problems may happen over hours, days, or weeks. They get worse 随着时间的推移. Problems may be:

  • Weakness 和 tingling in the legs, arms, 和 face
  • Pain in the legs or back
  • Problems walking or climbing stairs
  • Problems breathing
  • Eyesight problems
  • Problems swallowing, speaking, or chewing
  • Problems passing urine (peeing)

诊断

The doctor will ask about symptoms 和 past health. A physical exam will be done. This is often enough to diagnose Guillain-Barre syndrome. These tests may be done to support it:

治疗

The goal is to manage symptoms 和 help speed healing. Hospital care will be needed to watch for things like breathing 和 heart problems. Most people get better, but others may have lasting problems.

治疗 options are:

IV Immunoglobulin 治疗 (丙种球蛋白)

Immunoglobulins are proteins in the blood that fight infections. 丙种球蛋白 uses an IV to give a person proteins donated from a healthy person.

Plasmapheresis

Plasmapheresis removes blood from the body 和 passes it through a machine that separates blood cells. The cells are then returned to the body with new plasma. This may help a person get better faster.

治疗

Physical 和 occupational therapy may be needed. It can help a person with strength 和 motion. It can also help a person learn how to do daily tasks again.

Prevention

There are no guidelines to prevent this problem. However, flu vaccines may not be advised for:

  • People who had Guillain-Barre syndrome within 6 months of a flu vaccine, AND
  • Who are not at high risk for severe problems from the flu

This may help reduce their risk.

参考文献

  • Donofrio PD. Guillain-Barré Syndrome. Continuum (Minneap 明尼苏达州). 2017 Oct;23(5, Peripheral Nerve 和 Motor Neuron Disorders):1295-1309.
  • Guillain-Barre syndrome. Centers for Disease Control 和 Prevention website. 可用 at: http://www.疾病预防控制中心.gov/campylobacter/guillain-barre.html.
  • Guillain-Barre syndrome. EBSCO DynaMed website. 可用 at: http://www.力学.com/condition/guillain-barre-syndrome.
  • Guillain-Barre syndrome fact sheet. National Institute of Neurologica Disorders 和 中风 website. 可用 at: http://www.研究所.国家卫生研究院.gov/guillain-barre-syndrome-fact-sheet?search-term=Guillain-Barre.