Guillain-Barré Syndrome
Next Steps
Guillain-Barré Syndrome is treated at 澳门银河平台 Neurology's Neuromuscular Clinic.
About Guillain-Barré Syndrome
Definition
Guillain-Barré syndrome is a rare problem that causes the immune system to attack the nerves. This results in muscle weakness. It can range from mild to life-threatening. Most people will get better.
Nervous System |
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原因
The exact cause is not known. In some people, it is triggered by a recent infection.
Risk Factors
Guillain-Barré syndrome is more common in men. The risk gets higher with age. Other things that may raise the risk are:
- Recent infection
- Stress-related disorder
- Recent vaccination (rare)
症状
Problems may happen over hours, days, or weeks. They get worse 随着时间的推移. Problems may be:
- Weakness 和 tingling in the legs, arms, 和 face
- Pain in the legs or back
- Problems walking or climbing stairs
- Problems breathing
- Eyesight problems
- Problems swallowing, speaking, or chewing
- Problems passing urine (peeing)
诊断
The doctor will ask about symptoms 和 past health. A physical exam will be done. This is often enough to diagnose Guillain-Barre syndrome. These tests may be done to support it:
- Lumbar puncture—to test the fluid that protects the brain 和 spinal cord
- Nerve conduction 和 electromyography 研究
- Lung function tests
治疗
The goal is to manage symptoms 和 help speed healing. Hospital care will be needed to watch for things like breathing 和 heart problems. Most people get better, but others may have lasting problems.
治疗 options are:
IV Immunoglobulin 治疗 (丙种球蛋白)
Immunoglobulins are proteins in the blood that fight infections. 丙种球蛋白 uses an IV to give a person proteins donated from a healthy person.
Plasmapheresis
Plasmapheresis removes blood from the body 和 passes it through a machine that separates blood cells. The cells are then returned to the body with new plasma. This may help a person get better faster.
治疗
Physical 和 occupational therapy may be needed. It can help a person with strength 和 motion. It can also help a person learn how to do daily tasks again.
Prevention
There are no guidelines to prevent this problem. However, flu vaccines may not be advised for:
- People who had Guillain-Barre syndrome within 6 months of a flu vaccine, AND
- Who are not at high risk for severe problems from the flu
This may help reduce their risk.
参考文献
- Donofrio PD. Guillain-Barré Syndrome. Continuum (Minneap 明尼苏达州). 2017 Oct;23(5, Peripheral Nerve 和 Motor Neuron Disorders):1295-1309.
- Guillain-Barre syndrome. Centers for Disease Control 和 Prevention website. 可用 at: http://www.疾病预防控制中心.gov/campylobacter/guillain-barre.html.
- Guillain-Barre syndrome. EBSCO DynaMed website. 可用 at: http://www.力学.com/condition/guillain-barre-syndrome.
- Guillain-Barre syndrome fact sheet. National Institute of Neurologica Disorders 和 中风 website. 可用 at: http://www.研究所.国家卫生研究院.gov/guillain-barre-syndrome-fact-sheet?search-term=Guillain-Barre.